How long does it take for ivermectin to start killing parasites?

The parasite-killing effects of ivermectin 12 mg usually kick in within a day. Strongyloidiasis and onchocerciasis are among the parasitic illnesses that this potent antiparasitic medicine targets. It successfully paralyzes and kills the parasites by interfering with their nerve and muscle activity. While the majority of users report feeling better within a few days, certain infections may need up to a week for complete therapy.

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Ivermectin 12 mg typically begins to work within a few hours to a couple of days after taking it, depending on the type of parasite being targeted and the condition being treated.

Here's a general breakdown:
For intestinal parasites (e.g., strongyloidiasis): You may start seeing results within 1–2 days, but complete clearance can take a few days to a week.

For scabies or lice: Improvement may begin within 24–48 hours, with itching or skin irritation often persisting for a few days as dead mites or lice and their waste are cleared by the body.

For onchocerciasis (river blindness): Ivermectin quickly kills microfilariae (larval stage), and you may notice symptom relief within a few days, though multiple treatments are often required over time for long-term control.